Imperial College London is one of the world’s leading science focussed universities, and we are searching for an outstanding academic to join us as Research Associate.
This exciting, challenging and rewarding opportunity is based within the Vascular Science section of the National Heart and Lung Institute, Faculty of Meidicine which is based at our Hammersmith campus in the heart of London.
Imperial’s mission is to achieve enduring excellence in both research and education, and we are committed to making life changing advancements for the benefit of society. The main interests of Prof Randi’s group in Vascular Science focuses on to study the transcriptional and epigenetic drivers of endothelial lineage and regeneration.
Duties and responsibilities
Your core responsibilities will be to:
Work on blood outgrowth endothelial cells (BOEC), also known as endothelial colony forming cells (ECFC), and carry out genome-wide studies to identify lineage-specific transcriptional and epigenetic pathways to be exploited for regenerative medicine approaches. The project involves endothelial cell culture, basic transcriptional analysis, RNA seq and ChIP seq, bioinformatics analysis, validation using in vitro and ex vivo endothelial models; in vivo validation in models of vascular regeneration will be carried out in collaboration with others within the BHF Centre for Vascular Regeneration and the BHF Cardiovascular Regenerative Medicine Centre.
To succeed and excel in this role you will need:
A PhD in a relevant biological discipline and experience in transcription and epigenetics studies. Some knowledge of bioinformatic analysis of these datasets is essential. Previous experience in cell culture and BOEC/ECFC is desirable. The post will require collaboration with other groups both within and outside the Vascular Sciences department.
This post is full-time and fixed term for 18 months
The departmental research activities may be found at http://www.imperial.ac.uk/nhli/research/cardiovascular/vascular-science/
For an informal discussion about the post, please contact Prof Anna Randi, (firstname.lastname@example.org)
For further assistance, please contact Jinata Subba – email@example.com
Should you have any queries about the application process please contact firstname.lastname@example.org
Please note that job descriptions cannot be exhaustive and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.
All Imperial employees are expected to follow the 7 principles of Imperial Expectations:
Champion a positive approach to change and opportunity
Communicate regularly and effectively within, and across, teams
Consider the thoughts and expectations of others
Deliver positive outcomes
Encourage inclusive participation and eliminate discrimination
Develop and grow skills and expertise
Work in a planned and managed way
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